Demethoxycurcumin and its semisynthetic analogues as antitubercular agents.
نویسندگان
چکیده
Demethoxycurcumin, isolated from the rhizomes of Curcuma longa, was found to possess antitubercular activity against Mycobacterium tuberculosis H (37)Rv strain at 200 microg/mL. Derivatisation of this active principle yielded a potent agent 6, exhibiting considerable activity with a minimum inhibitory concentration (MIC) value of 7.8 microg/mL. H (37)Rv:Mycobacterium tuberculosis H (37)Rv strain MIC:minimum inhibitory concentration.
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عنوان ژورنال:
- Planta medica
دوره 74 15 شماره
صفحات -
تاریخ انتشار 2008